Course Content
Module 1: Basic ECMO
Module I: Extracorporeal Membrane Oxygenation Basics (ECMO Basics) This module covers the foundational knowledge of ECMO, including circuit physiology, components, and basic ECMO management. Duration: 3 Weeks (Course weeks 1 to 3) Week 1: Introduction to ECMO Week 2: ECMO Physiology & Circuit Management Week 3: ECMO Complications and Troubleshooting Module I Pretest: 30 MCQs
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Module II: Veno-venous Extracorporeal Membrane Oxygenation (VV ECMO)
This module focuses on the use of VV ECMO in patients with respiratory failure. Topics include ARDS management, VV ECMO cannulation strategies, and VV ECMO troubleshooting. Duration: 3 Weeks (Course weeks 4 to 6) Module II Pretest: 30 MCQs Week 4: VV ECMO Fundamentals Start Date: July 20, 2025 a. Respiratory failure and ARDS management (Ahmed Magdey) b. Evidence for VV ECMO use and landmark trials (Hesham Faisal) c. VV ECMO cannulation techniques and pros and cons of different VV ECMO configuration choices (Moustafa Esam) d. ECMO Retrieval and Patient Transport on ECMO (Ahmed Labib)
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Module III: Veno-arterial Extracorporeal Membrane Oxygenation (VA ECMO)
This module focuses on VA ECMO for cardiogenic shock, including cannulation strategies, LV unloading, and advanced applications. Duration: 3 Weeks (Course weeks 7 to 9) Module II Pretest: 30 MCQs
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Extra Corporeal Membrane Oxygenation (ECMO) and Mechanical Circulatory Support (MCS) course (Copy 4)

ECMO & MCS Course Summary: Drainage Insufficiency and Cannulation Strategies

 Learning Objectives for VV ECMO Session

  • Understand VV ECMO cannulation strategies.

  • Explore cannula design and sizing principles.

  • Recognize and manage recirculation and drainage insufficiency.

 Key Concepts in VV ECMO Cannulation

🔸 ECMO Overview

  • VV ECMO = “lung replacement,” supports gas exchange only.

  • VA ECMO = supports both cardiac and pulmonary functions.

🔸 Venous Drainage Site Selection

  • Blood can be drained from SVC or IVC; IVC is preferred (drains ~2/3 of venous return).

  • Drainage cannula typically placed in R femoral vein, returning oxygenated blood via internal jugular vein.

🔸 Cannula Sizing and Flow Physics

  • Based on Poiseuille’s Law: shorter, wider cannulas reduce resistance and improve drainage.

  • Choose cannula size <80% of vein diameter.

  • 1 French = 0.33 mm (e.g., 23 Fr ≈ 7.6 mm outer diameter).

🔧 Cannulation Techniques

  • Ultrasound guidance: Now standard of care to reduce vascular complications.

  • Fluoroscopy (C-arm): Use in cath lab or hybrid OR to ensure correct guidewire and cannula path.

  • Echocardiography (TEE/bedside): Mandatory for dual-lumen cannula placement; strongly recommended for all.

Dual Cannula Configurations

  • Femoral-femoral: Drain via one femoral vein, return via contralateral femoral.

  • Femoral-jugular: Drain via femoral vein, return via internal jugular vein.

  • Drainage cannula: Multi-stage, 20 cm of side holes to ensure hepatic vein drainage.

  • Return cannula: Short tip-focused cannula, positioned near tricuspid valve.

Single Dual-Lumen Cannula (e.g., Avalon)

  • Single access via right IJ vein.

  • Drainage ports in IVC and SVC, infusion directed toward tricuspid valve.

  • Requires expert TEE guidance.

  • Pros: Enables mobilization, fewer access sites.

  • Cons: Technically challenging, risk of misdirection or cardiac injury.

🔴 Recirculation: Detection and Management

What is Recirculation?

  • Occurs when oxygenated blood from return cannula is immediately sucked into drainage cannula.

  • Results in inefficient oxygen delivery.

Causes:

  • Cannulas too close together (<8–10 cm apart).

  • Improper orientation (e.g., not facing tricuspid valve).

  • Excessively high flows in circuit.

Diagnosis:

  • Persistent hypoxia despite adequate ECMO flow and functioning membrane.

  • High post-oxygenator saturation (>80%) with low systemic saturation.

Troubleshooting Hypoxia

  1. Confirm color of lines: Drain = blue, Return = red.

  2. Gas flow = blood flow (1:1 ratio).

  3. Blender set to 100% O₂.

  4. Ensure flow calibration completed.

  5. Inspect membrane for clot burden.

  6. Check for access insufficiency: unstable flows, swinging pressures, low inlet pressures.

  7. Test pre-oxygenator venous saturation:

    • <60% → high oxygen consumption.

    • 80% → recirculation.

✅ Summary Comparison: Dual Lumen vs Dual Cannula VV ECMO

🏁 Final Takeaways

  • All cannulation strategies are valid if appropriately executed.

  • Positioning and imaging are key to avoid recirculation and access insufficiency.

  • Use simulation, echo, and flow monitoring to optimize patient outcomes.

  • Build team competency with checklists, structured training, and interdisciplinary collaboration.

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